Linear synthesis of the branched pentasaccharide repeats of O-antigens from Shigella flexneri 1a and 1b demonstrating the major steric hindrance associated with type-specific glucosylation-Reference-Cited by-同舟云学术

Linear synthesis of the branched pentasaccharide repeats of O-antigens from Shigella flexneri 1a and 1b demonstrating the major steric hindrance associated with type-specific glucosylation

Published:2014 Issue:39 Volume:12 Page:7728-7749
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hargreaves Jason M.¹²³⁴¹,Le Guen Yann¹²³⁴¹,Guerreiro Catherine¹²³⁴¹,Descroix Karine¹²³⁴¹,Mulard Laurence A.¹²³⁴¹

Affiliation:

1. Institut Pasteur

2. Unité de Chimie des Biomolécules

3. 75724 Paris Cedex 15, France

4. CNRS UMR3523

Abstract

Shigella flexneri serotypes 1b and 1a are Gram-negative enteroinvasive bacteria causing shigellosis in humans.

Funder

Institut Pasteur

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB01200C

Reference65 articles.

1. Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

2. Progress and pitfalls in Shigella vaccine research

3. A Synthetic Carbohydrate-Protein Conjugate Vaccine Candidate againstShigella flexneri2a Infection

4. Characterization of Functional Oligosaccharide Mimics of theShigella flexneriSerotype 2a O-Antigen: Implications for the Development of a Chemically Defined Glycoconjugate Vaccine

5. Shigella flexneriO-antigens revisited: final elucidation of the O-acetylation profiles and a survey of the O-antigen structure diversity

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