Single-molecule evidence for a chemical ratchet in binding between the <i>cam</i> repressor and its operator-Reference-Cited by-同舟云学术

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Single-molecule evidence for a chemical ratchet in binding between the cam repressor and its operator

Published:2022 Issue:36 Volume:14 Page:13315-13323
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Kabata Hiroyuki¹^ORCID,Aramaki Hironori²^ORCID,Shimamoto Nobuo¹^ORCID

Affiliation:

1. National Institute of Genetics, and Department of Genetics, School of Life Science, The Graduate University for Advanced Studies, SOKENDAI, 1111 Yata, Mishima, Shizuoka, 411-8540, Japan

2. Department of Molecular and Life Science, Faculty of Pharmacy, Daiichi University of Pharmacy, 22-1 Tamagawa-cho, Minami-ku, Fukuoka, 815-8511, Japan

Abstract

The chemical ratchet, a mechanism indifferent to detailed balance, is evidenced by a single-molecule experiment involving the binding of a bacterial repressor to its operator.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NR/D2NR03454A

Reference28 articles.

1. Facilitated Target Location in Biological Systems

2. Molecular mechanism of promoter selection in gene transcription. II. Kinetic evidence for promoter search by a one-dimensional diffusion of RNA polymerase molecule along the DNA template.

3. Pausing of the Restriction Endonuclease EcoRI during Linear Diffusion on DNA

4. Visualization of Single Molecules of RNA Polymerase Sliding Along DNA

5. One-dimensional Diffusion of Proteins along DNA

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