Cleavage of the C–C triple bond of ketoalkynes: synthesis of 4(3H)-quinazolinones
Author:
Affiliation:
1. Key Laboratory of Xiamen Marine and Gene Drugs
2. Institutes of Molecular Medicine and School of Biomedical Sciences
3. Huaqiao University & Engineering Research Center of Molecular Medicine
4. Ministry of Education
5. Xiamen 361021
Abstract
A novel strategy to 4(3H)-quinazolinones from ketoalkynes and o-aminobenzamides through C–C triple bond fragmentation and two C–N bond formations under external oxidant and metal free conditions.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/QO/C4QO00260A
Reference33 articles.
1. Two New Pyrroloquinazolinoquinoline Alkaloids from Peganum nigellastrum
2. Synthesis of some new 4(3H)-quinazolinone-2-carboxaldehyde thiosemicarbazones and their metal complexes and a study on their anticonvulsant, analgesic, cytotoxic and antimicrobial activities – Part-1
3. Design, synthesis and antiviral activity of novel quinazolinones
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