The Effect of Consuming Spices on Vascular Function

Abstract

Cardiovascular disease is the leading cause of death globally. Vascular dysfunction is a major contributor to cardiovascular risk. Oxidative stress and inflammation play key roles in vascular dysfunction. Studies have thus far reported the effects of consuming spices (and herbs) on improving vascular function and reducing oxidative stress and inflammation. This review aims to comprehensively summarize the results of human intervention studies that evaluated the effect of spices (cinnamon, garlic, ginger, and turmeric/curcumin) on vascular function and biomarkers of oxidative stress and inflammation. Moreover, the mechanism(s) of action that may underlie the effect of these spices on vascular function is(are) discussed.