AccuTOF-DART for Rapid Presumptive Screening of Drugs of Abuse

Abstract

Methods described in this chapter enable rapid and confident drug identification in the forensic laboratory. The use of direct analysis in real time ionization with high-resolution time-of-flight mass spectrometry to generate accurate mass and fragment ions is described with examples covering the detection of both major and minor compounds present in samples. The development of publicly available drug libraries and spectrum search technology is also reported to complete this chapter.