Affiliation:
1. JEOL USA, Inc. 11 Dearborn Road Peabody MA 01960 USA cody@jeol.com
Abstract
A sample preparation method that removes chemical interferences and concentrates the analytes of interest can greatly enhance the value of ambient ionization methods by improving selectivity and reducing detection limits. Because solid-phase microextraction (SPME) is rapid, inexpensive, and simple to use, it is an ideal choice of a sample preparation method for use with ambient ionization mass spectrometry. This chapter focuses on the combination of SPME and one of the most widely used ambient ionization methods: Direct Analysis in Real Time (DART).
Publisher
The Royal Society of Chemistry