Advances in the Analysis of Veterinary Drug Residues in Animal Origin Food by SPME

Abstract

This chapter presents a comprehensive review of recent developments of solid-phase microextraction (SPME) applications for screening and quantitative analysis of multi-class multi-residue veterinary drugs in animal-derived matrices. We briefly introduce the most commonly performed sample preparation techniques for multi-class multi-residue methods and pay particular attention to alternative approaches based on the most recent SPME developments aimed to reduce sample turnaround time, minimize experimental errors, and lower the cost per analysis via automation and high-throughput sample preparation. Furthermore, this chapter examines the latest developments in the field of rapid screening and quantitation of multi-residue veterinary drugs in animal-derived samples by means of direct coupling of SPME to different ambient ionization techniques, namely coated blade spray (CBS) and direct analysis in real time (DART).