Graphene-based Nanocomposites for Hormone Detection

Author:

Ilie-Mihai R.-M.1,Gheorghe D.-C.1,Stefan-van Staden R.-I.1

Affiliation:

1. Laboratory of Electrochemistry and PATLAB, National Institute of Research for Electrochemistry and Condensed Matter, 202 Splaiul Independentei Str., 060021 Bucharest, Romania

Abstract

Hormones serve important roles in many physiological processes, such as stress adaption, blood pressure regulation, reproductive cycles, and even body odor, making their monitoring of great importance. The functioning of particular cells and organs in the human body is regulated and controlled by hormones at incredibly low levels. A variety of disorders can be brought on by an imbalance in hormones. Tools for detecting hormones have therefore been developed, notably in the recent decade. As a result, efforts have been made to create a very sensitive instrument capable of detecting the minute amounts of hormones needed to regulate and govern human metabolism. Common methods of detection need extensive time and resources to set up and analyze. Since electrochemical techniques often outperform more conventional, time-consuming methods (such as enzyme-linked immunosorbent assay) regarding sensitiveness, selectivity, and effectiveness in a short amount of time, they have become the preferred methods for hormone sensing. This chapter’s focus is on the use of graphene-nanocomposites in the electrochemical detection of several hormones. Numerous electroanalytical methods have been used in order to examine hormones and learn more about their structural features and biological importance.

Publisher

Royal Society of Chemistry

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