The Circadian–Hypoxia Link-Reference-Cited by-同舟云学术

The Circadian–Hypoxia Link

Published:2024-02-23 Issue: Volume: Page:136-159
ISSN:
Container-title:Chronobiology and Chronomedicine
language:en
Short-container-title:

Author:

Oyama Yoshimasa¹,Walker Lori A.²,Eckle Tobias³

Affiliation:

1. aDepartment of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan

2. bDivision of Cardiology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA

3. cDepartment of Anesthesiology, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA

Abstract

Circadian rhythm and hypoxia-mediated adaptation to myocardial ischaemia are linked on a molecular level. Targeting circadian rhythms via the dominant zeitgeber, light, can manipulate hypoxic pathways and provide protection against cardiovascular diseases. Understanding the circadian–hypoxia link reveals novel insights into cardiovascular therapeutics, including how the use of intense light or circadian amplitude enhancing drugs helps maintain or restore heart health.

Publisher

Royal Society of Chemistry

Link

https://books.rsc.org/books/edited-volume/chapter-pdf/1808175/bk9781839167553-00136.pdf

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