Design and fabrication of a liver-on-a-chip platform for convenient, highly efficient, and safe in situ perfusion culture of 3D hepatic spheroids-Reference-Cited by-同舟云学术

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Design and fabrication of a liver-on-a-chip platform for convenient, highly efficient, and safe in situ perfusion culture of 3D hepatic spheroids

Published:2018 Issue:17 Volume:18 Page:2547-2562
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Ma Li-Dong¹²³⁴⁵,Wang Yi-Tong¹²³⁴⁵,Wang Jing-Rong¹²³⁴⁵^ORCID,Wu Jian-Lin¹²³⁴⁵,Meng Xian-Sheng⁶⁷⁸⁵,Hu Ping⁹¹⁰¹¹⁵,Mu Xuan¹²¹³¹⁴¹⁵^ORCID,Liang Qiong-Lin¹⁶¹⁷¹⁸⁵^ORCID,Luo Guo-An¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Quality Research in Chinese Medicine

2. Macau Institute for Applied Research in Medicine and Health

3. Macau University of Science and Technology

4. Macau

5. China

6. School of Pharmacy

7. Liaoning University of Traditional Chinese Medicine

8. Dalian 116600

9. School of Chemistry and Molecular Engineering

10. East China University of Science and Technology

11. Shanghai 200237

12. Department of Biomedical Engineering

13. Tufts University

14. Medford

15. USA

16. Department of Chemistry

17. Tsinghua University

18. Beijing 100084

Abstract

This work presents a biomimetic and reversibly-assembled liver-on-a-chip platform for building a 3D liver spheroid model.

Funder

Fundo para o Desenvolvimento das Ciências e da Tecnologia

Ministry of Science and Technology of the People's Republic of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2018/LC/C8LC00333E

Reference46 articles.

1. Microfluidic organs-on-chips

2. An extracellular matrix microarray for probing cellular differentiation

3. Microscale culture of human liver cells for drug development

4. A three-dimensional co-culture of HepG2 spheroids and fibroblasts using double-layered fibrous scaffolds incorporated with hydrogel micropatterns

5. The third dimension bridges the gap between cell culture and live tissue

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