Synthesis of a bicyclic oxo-γ-lactam from a simple caprolactam derivative-Reference-Cited by-同舟云学术

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Synthesis of a bicyclic oxo-γ-lactam from a simple caprolactam derivative

Published:2017 Issue:18 Volume:41 Page:9984-9989
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Weck Christian¹²³⁴⁵,Obst Franziska¹²³⁴,Nauha Elisa⁶⁷⁸⁹¹⁰,Schofield Christopher J.¹¹¹²¹³¹⁴¹⁰^ORCID,Gruber Tobias¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Organic Chemistry

2. Technische Universität Bergakademie Freiberg

3. Freiberg/Sachsen

4. Germany

5. School of Pharmacy

6. School of Chemistry

7. University of Lincoln

8. Joseph Banks Laboratories

9. Lincoln LN6 7DL

10. UK

11. Department of Chemistry

12. Chemistry Research Laboratory

13. University of Oxford

14. Oxford OX1 3TA

Abstract

Reaction of caprolactams with an axial ester substituent with base gives the 6-azabicyclo-[3.2.1]octane ring system via Dieckmann cyclization.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NJ/C7NJ02348K

Reference26 articles.

1. The road to avibactam: the first clinically useful non-β-lactam working somewhat like a β-lactam

2. In vitro activity of the -lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases

3. Avibactam is a covalent, reversible, non- -lactam -lactamase inhibitor

4. Carbamoyl Radical‐Mediated Synthesis and Semipinacol Rearrangement of β‐Lactam Diols

5. Synthesis and absolute configuration of the Aristotelia alkaloid peduncularine

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Does the Exception Prove the Rule? A Comparative Study of Supramolecular Synthons in a Series of Lactam Esters;Crystal Growth & Design;2019-03-26

2. Missing Link in the Homologous Series of Lactams: The X-ray Structure of Valerolactam;Crystal Growth & Design;2018-11-15

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