Ginnalin A from Kujin tea (Acer tataricum subsp. ginnala) exhibits a colorectal cancer chemoprevention effect via activation of the Nrf2/HO-1 signaling pathway-Reference-Cited by-同舟云学术

Ginnalin A from Kujin tea (Acer tataricum subsp. ginnala) exhibits a colorectal cancer chemoprevention effect via activation of the Nrf2/HO-1 signaling pathway

Published:2018 Issue:5 Volume:9 Page:2809-2819
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Bi Wu¹²³⁴⁵^ORCID,He Chun-nian⁶⁷⁸⁹¹⁰,Li Xiao-xiao¹²³⁴⁵,Zhou Liu-ying¹²³⁴⁵,Liu Rui-jie¹²³⁴⁵,Zhang Sai¹²³⁴⁵,Li Guo-qing¹¹¹²¹³¹⁴¹⁵,Chen Zhu-chu¹²³⁴⁵,Zhang Peng-fei¹²³⁴⁵

Affiliation:

1. Key Laboratory of Cancer Proteomics of Chinese Ministry of Health

2. Xiangya Hospital

3. Central South University

4. Changsha

5. P.R. China

6. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine

7. Ministry of Education

8. Institute of Medicinal Plant Development

9. Chinese Academy of Medical Science and Peking Union Medical College

10. Beijing

11. Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study

12. School of Pharmacy and Life Science

13. University of South China

14. Hengyang 421001

15. China

Abstract

Ginnalin A may activate the Nrf2 signaling pathway through the upregulation of p62 and the inhibition of Keap1 to exert a cancer chemoprevention effect.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Natural Science Foundation of Hunan Province

Education Department of Hunan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/FO/C8FO00054A

Reference45 articles.