Microwave-assisted synthesis of ruthenium(ii) complexes containing levofloxacin-induced G2/M phase arrest by triggering DNA damage-Reference-Cited by-同舟云学术

Microwave-assisted synthesis of ruthenium(ii) complexes containing levofloxacin-induced G2/M phase arrest by triggering DNA damage

Published:2021 Issue:8 Volume:11 Page:4444-4453
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Liu Ruotong¹²³⁴⁵,Yuan Chanling⁴⁵⁶³,Feng Yin¹²³,Qian Jiayi⁴⁵⁶³,Huang Xiaoting⁴⁵⁶³,Chen Qiutong⁷⁸⁹³,Zhou Shuyuan¹⁰⁶³,Ding Yin¹²³,Zhai Bingbing⁴⁵⁶³,Mei Wenjie⁴⁵⁶³¹⁰^ORCID,Yao Liangzhong¹²³

Affiliation:

1. The First Affiliation Hospital of Guangdong Pharmaceutical University

2. Guangzhou 510062

3. China

4. School of Pharmacy

5. Guangdong Pharmaceutical University

6. Guangzhou 510006

7. School of Politics and Public Administration

8. South China Normal University

9. Guangzhou

10. Guangdong Province Engineering Technology Centre for Molecular Probe and Bio-Medical Imaging

Abstract

This study showed that levofloxacin-based ruthenium(ii) complex 2 effectively inhibited the growth of A549 cells by inducing G2/M phase arrest through triggering DNA damage.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA09418H

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