Facile solid phase peptide synthesis with a Re-lysine conjugate generated via a one-pot procedure

Author:

Chanawanno Kullapa123,Caporoso Joel123,Kondeti Vinay123,Paruchuri Sailaja123,Leeper Thomas C.123,Herrick Richard S.145,Ziegler Christopher J.123

Affiliation:

1. Department of Chemistry

2. University of Akron

3. Akron, USA

4. College of the Holy Cross

5. Worcester, USA

Abstract

We have synthesized a Re(CO)3-modified lysine via a one-pot Schiff base formation reaction that can be used in the solid phase peptide synthesis of peptides, and demonstrated uptake into human umbilical vascular endothelial cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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