The synthesis of diverse benzazepinoindoles <i>via</i> gold-catalyzed post-Ugi alkyne hydroarylation/Michael addition sequence-Reference-Cited by-同舟云学术

The synthesis of diverse benzazepinoindoles via gold-catalyzed post-Ugi alkyne hydroarylation/Michael addition sequence

Published:2022 Issue:17 Volume:9 Page:4619-4624
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Liu Chao¹,Van Meervelt Luc²,Peshkov Vsevolod A.³⁴^ORCID,Van der Eycken Erik V.¹⁵^ORCID

Affiliation:

1. Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001, Leuven, Belgium

2. Biomolecular Architecture, Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001, Leuven, Belgium

3. College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Dushu Lake Campus, Suzhou 215123, P. R. China

4. Department of Chemistry, School of Sciences and Humanities, Nazarbayev University, 53 Kabanbay Batyr Ave, Nur-Sultan 010000, Republic of Kazakhstan

5. Peoples’ Friendship University of Russia (RUDN University), Miklukho-Maklaya Street 6, Moscow, 117198, Russia

Abstract

By combining an Ugi-4CR and a gold-catalyzed cascade cyclization, diverse benzazepinoindoles are assembled in a step-economical, chemo- and regioselectivity fashion.

Funder

China Scholarship Council

Herculesstichting

Nazarbayev University

Fonds Wetenschappelijk Onderzoek

KU Leuven

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO00810F