Diastereodivergent aminocatalyzed spirocyclization strategies using 4-alkylideneisoxazol-5-ones and methyl vinyl ketones-Reference-Cited by-同舟云学术

Diastereodivergent aminocatalyzed spirocyclization strategies using 4-alkylideneisoxazol-5-ones and methyl vinyl ketones

Published:2020 Issue:22 Volume:7 Page:3599-3607
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

da Silva Amanda F.¹²³⁴^ORCID,Leonarczyk Ives A.⁵⁶⁷⁸⁴,Ferreira Marco A. B.⁵⁶⁷⁸⁴,Jurberg Igor D.¹²³⁴^ORCID

Affiliation:

1. Institute of Chemistry

2. State University of Campinas

3. Campinas

4. Brazil

5. Centre of Excellence for Research in Sustainable Chemistry (CERSusChem)

6. Department of Chemistry

7. Federal University of São Carlos

8. São Carlos

Abstract

Diasterodivergent aminocatalyzed approaches starting from 4-alkylideneisoxazol-5-ones and methyl vinyl ketones have been developed for the synthesis of racemic 6,10-cis-spiroisoxazol-5-ones and highly enantioenriched 6,10-trans-spiroisoxazol-5-ones.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00779J

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