Borane-catalyzed metal-free hydrogenation of 2,7-disubstituted 1,8-naphthyridines-Reference-Cited by-同舟云学术

Borane-catalyzed metal-free hydrogenation of 2,7-disubstituted 1,8-naphthyridines

Published:2016 Issue:28 Volume:14 Page:6683-6686
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wang Wei¹²³⁴⁵,Feng Xiangqing¹²³⁴⁵,Du Haifeng¹²³⁴⁵

Affiliation:

1. Beijing National Laboratory of Molecular Sciences

2. CAS Key Laboratory of Molecular Recognition and Function

3. Institute of Chemistry

4. Chinese Academy of Sciences

5. Beijing 100190

Abstract

Metal-free hydrogenation of 2,7-disubstituted 1,8-naphthyridines was realized to furnish 1,2,3,4-tetrahydro-1,8-naphthyridines in high yields with up to 74% ee.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01172A

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5. Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK

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