A novel bis(pinacolato)diboron-mediated N–O bond deoxygenative route to C6 benzotriazolyl purine nucleoside derivatives-Reference-Cited by-同舟云学术

A novel bis(pinacolato)diboron-mediated N–O bond deoxygenative route to C6 benzotriazolyl purine nucleoside derivatives

Published:2016 Issue:29 Volume:14 Page:7069-7083
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Basava Vikram¹²³⁴,Yang Lijia¹²³⁴,Pradhan Padmanava¹²³⁴,Lakshman Mahesh K.¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. The City College of New York

3. New York

4. USA

5. The Ph.D. Program in Chemistry

Abstract

O⁶-(Benzotriazol-1-yl)purine nucleosides, containing a C–O–N bond, undergo facile reduction of the N–O bond with (pinB)₂and Cs₂CO₃.Viathis approach a series of 6-(benzotriazol-1-yl)purine nucleosides were synthesized and the mechanism has been investigated.

Funder

National Institute on Minority Health and Health Disparities

Division of Chemistry

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01170E

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