The anti-atherosclerotic effect of tanshinol borneol ester using fecal metabolomics based on liquid chromatography-mass spectrometry-Reference-Cited by-同舟云学术

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The anti-atherosclerotic effect of tanshinol borneol ester using fecal metabolomics based on liquid chromatography-mass spectrometry

Published:2016 Issue:3 Volume:141 Page:1112-1120
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Jia Pu¹²³⁴⁵,Wang Shixiang¹²³⁴⁵,Xiao Chaoni¹²³⁴⁵,Yang Lumeng¹²³⁴⁵,Chen Yongyong¹²³⁴⁵,Jiang Wei⁶⁷⁸⁹⁵,Zheng Xiaopu¹⁰¹¹¹²⁴⁵,Zhao Guifang¹²³⁴⁵,Zang Weijin¹³¹⁴¹²⁴⁵,Zheng Xiaohui¹²³⁴⁵

Affiliation:

1. Key Laboratory of Resource Biology and Biotechnology in Western China

2. College of Life Sciences

3. Northwest University

4. Xi'an

5. China

6. Pharmacy Department

7. Tangdu Hospital

8. Fourth Military Medical University

9. Xi'an, 710038

10. Department of Critical Care Medicine

11. the First Hospital

12. Xi'an Jiaotong University

13. Department of Pharmacology

14. College of Medicine

Abstract

This study revealed the potential biomarkers in rats’ feces associated with atherosclerosis and anti-atherosclerosis of DBZ using LC-MS metabolomics.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/AN/C5AN01970B

Reference51 articles.

1. Metabolism of Tanshinol Borneol Ester in Rat and Human Liver Microsomes

2. Antioxidant and cardioprotective effects of Danshensu (3-(3, 4-dihydroxyphenyl)-2-hydroxy-propanoic acid from Salvia miltiorrhiza) on isoproterenol-induced myocardial hypertrophy in rats

3. Down-Regulation of CD40 Gene Expression and Inhibition of Apoptosis with Danshensu in Endothelial Cells

4. Cardioprotective effect of Danshensu against myocardial ischemia/reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation

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