Auto-affitech: an automated ligand binding affinity evaluation platform using digital microfluidics with a bidirectional magnetic separation method-Reference-Cited by-同舟云学术

Auto-affitech: an automated ligand binding affinity evaluation platform using digital microfluidics with a bidirectional magnetic separation method

Published:2020 Issue:9 Volume:20 Page:1577-1585
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Guo Jingjing¹²³⁴⁵,Lin Li¹²³⁴⁵,Zhao Kaifeng¹²³⁴⁵,Song Yanling⁶⁷⁸⁹¹⁰^ORCID,Huang Mengjiao¹²³⁴⁵,Zhu Zhi¹²³⁴⁵^ORCID,Zhou Leiji¹²³⁴⁵^ORCID,Yang Chaoyong¹²³⁴⁵^ORCID

Affiliation:

1. MOE Key Laboratory of Spectrochemical Analysis & Instrumentation

2. Key Laboratory of Chemical Biology of Fujian Province

3. State Key Laboratory of Physical Chemistry of Solid Surfaces

4. Collaborative Innovation Center of Chemistry for Energy Materials

5. College of Chemistry and Chemical Engineering

6. Institute of Molecular Medicine

7. Renji Hospital

8. School of Medicine

9. Shanghai Jiao Tong University

10. Shanghai

Abstract

An automated ligand binding affinity evaluation platform using digital microfluidics with a bidirectional magnetic separation method that reduces the bead loss.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/D0LC00024H

Reference48 articles.

1. Molecular recognition in antibody-antigen complexes

2. Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism

3. Adaptive Recognition by Nucleic Acid Aptamers