Chemoselective and one-pot synthesis of novel coumarin-based cyclopenta[<i>c</i>]pyrans <i>via</i> base-mediated reaction of α,β-unsaturated coumarins and β-ketodinitriles-Reference-Cited by-同舟云学术

Chemoselective and one-pot synthesis of novel coumarin-based cyclopenta[c]pyrans via base-mediated reaction of α,β-unsaturated coumarins and β-ketodinitriles

Published:2022 Issue:12 Volume:12 Page:7262-7267
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Farajpour Behnaz¹^ORCID,Alizadeh Abdolali¹^ORCID

Affiliation:

1. Department of Chemistry, Tarbiat Modares University, P. O. Box 14115-175, Tehran, Iran

Abstract

In this paper, the base-mediated cascade reactions of 4-chloro-3-vinyl coumarins with β-ketodinitriles were demonstrated, allowing the efficient synthesis of coumarin-based cyclopenta[c]pyran-7-carbonitriles with interesting chemoselectivity.

Funder

Tarbiat Modares University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA00594H

Reference42 articles.

1. Coumarin–chalcone hybrids: promising agents with diverse pharmacological properties

2. Synthesis, biological evaluation and molecular docking of novel chalcone–coumarin hybrids as anticancer and antimalarial agents

3. Synthesis and biological evaluation of novel formyl-pyrazoles bearing coumarin moiety as potent antimicrobial and antioxidant agents