Bisindole-based small molecules as transmembrane anion transporters and potential anticancer agents-Reference-Cited by-同舟云学术

Bisindole-based small molecules as transmembrane anion transporters and potential anticancer agents

Published:2024 Issue:24 Volume:22 Page:4987-4992
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Salunke Swati Bansi¹^ORCID,Save Shreyada N.²^ORCID,Roy Naveen J.¹^ORCID,Naorem Ronedy¹^ORCID,Sharma Shilpy²^ORCID,Talukdar Pinaki¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Science Education and Research (IISER) Pune, Dr. Homi Bhabha Road, Pashan, Pune 411008, Maharashtra, India

2. Department of Biotechnology, Savitribai Phule Pune University (Formerly University of Pune), Pune 411007, Maharashtra, India

Abstract

A bisindole-based transmembrane anion antiporter, selectively toxic to the MCF-7 cancer cells, where chloride transport-induced homeostasis disruption triggered mitochondrial membrane depolarization, ROS generation, and lysosomal deacidification.

Funder

Science and Engineering Research Board

Indian Institute of Science Education and Research Pune

University Grants Commission

Department of Science and Technology, Ministry of Science and Technology

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00554F

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