Tailoring amphotericin B as an ionic liquid: an upfront strategy to potentiate the biological activity of antifungal drugs-Reference-Cited by-同舟云学术

Tailoring amphotericin B as an ionic liquid: an upfront strategy to potentiate the biological activity of antifungal drugs

Published:2021 Issue:24 Volume:11 Page:14441-14452
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Hartmann Diego O.¹²³⁴^ORCID,Shimizu Karina⁵⁶⁷⁸⁴^ORCID,Rothkegel Maika¹²³⁴^ORCID,Petkovic Marija¹²³⁴^ORCID,Ferraz Ricardo⁹¹⁰¹¹⁴¹²^ORCID,Petrovski Željko¹²¹³¹⁴¹⁵⁴^ORCID,Branco Luís C.¹²¹³¹⁴¹⁵⁴^ORCID,Canongia Lopes José N.⁵⁶⁷⁸⁴^ORCID,Silva Pereira Cristina¹²³⁴^ORCID

Affiliation:

1. Instituto de Tecnologia Química e Biológica António Xavier

2. Universidade Nova de Lisboa (ITQB NOVA)

3. Oeiras

4. Portugal

5. Centro de Química Estrutural

6. Instituto Superior Técnico

7. Universidade de Lisboa

8. 1049-001 Lisboa

9. Ciências Químicas e das Biomoléculas (CQB) e Centro de Investigação em Saúde e Ambiente (CISA)

10. Escola Superior de Saúde do Instituto Politécnico do Porto

11. 4400-330 Porto

12. LAQV-REQUIMTE

13. Departamento de Química

14. Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa

15. 2829-516 Caparica

Abstract

Antifungal susceptibility assays and molecular dynamics simulation studies reveal a novel cetylpyridinium amphotericin B ionic liquid formulation with dual functionality: antifungal and antibacterial activities.

Funder

Fundação para a Ciência e a Tecnologia

H2020 European Research Council

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA00234A

Reference58 articles.

1. Hidden Killers: Human Fungal Infections