Widely applicable background depletion step enables transaminase evolution through solid-phase screening
Author:
Affiliation:
1. University of Nottingham
2. School of Chemistry
3. Nottingham NG7 2RD
4. United Kingdom
5. Structural Biology Unit
6. Dep. Biosciences
7. Università degli Studi di Milano
8. 20133 Milano
9. Italy
10. University of Bern
Abstract
Directed evolution of transaminases is a widespread technique in the development of highly sought-after biocatalysts for industrial applications.
Funder
Biotechnology and Biological Sciences Research Council
University of Nottingham
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/SC/C8SC05712E
Reference38 articles.
1. Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts
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5. Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin
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