The protein corona determines the cytotoxicity of nanodiamonds: implications of corona formation and its remodelling on nanodiamond applications in biomedical imaging and drug delivery

Author:

Khanal Dipesh12345,Lei Qingyu12345,Pinget Gabriela16735,Cheong Daniel A.891011,Gautam Archana121314,Yusoff Ridhwan121314,Su Bowyn12345,Yamaguchi Seiji15161718,Kondyurin Alexey19120,Knowles Jonathan C.2122232425ORCID,Georgiou George21222324,Macia Laurence16735,Jang Jun-Hyeog26272829,Ramzan Iqbal13420,Ng Kee Woei1213143014ORCID,Chrzanowski Wojciech12345ORCID

Affiliation:

1. The University of Sydney

2. Sydney Nano Institute

3. Faculty of Medicine and Health

4. Sydney Pharmacy School

5. Sydney

6. Charles Perkins Centre

7. School of Medical Sciences

8. The University of Oklahoma

9. Stephenson School of Biomedical Engineering

10. Oklahoma

11. USA

12. Nanyang Technological University

13. School of Materials Science and Engineering

14. Singapore

15. Department of Biomedical Sciences

16. College of Life and Health Sciences

17. Chubu University

18. Japan

19. School of Physics

20. Australia

21. Division of Biomaterials and Tissue Engineering

22. University College London Eastman Dental Institute

23. London WC1X 8LD

24. UK

25. The Discoveries Centre for Regenerative and Precision Medicine

26. Department of Biochemistry

27. Inha University School of Medicine

28. Incheon 22212

29. Korea

30. Skin Research Institute of Singapore

Abstract

Protein corona determines fate and cytotoxicity of nanoparticles in biological systems.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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