One-pot cascade synthesis of azabicycles via the nitro-Mannich reaction and N-alkylation-Reference-Cited by-同舟云学术

One-pot cascade synthesis of azabicycles via the nitro-Mannich reaction and N-alkylation

Published:2018 Issue:5 Volume:16 Page:707-711
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Disadee Wannaporn¹²³⁴^ORCID,Ruchirawat Somsak¹²³⁴⁵

Affiliation:

1. Laboratory of Medicinal Chemistry

2. Chulabhorn Research Institute

3. Bangkok 10210

4. Thailand

5. Program in Chemical Biology

Abstract

A cascade of double intramolecular cyclizations via the nitro-Mannich reaction and N-alkylation provides direct access to various ring systems of azabicycles.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C7OB03104A

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4. (+)-Laburnamine, a Natural Selective Ligand and Partial Agonist for the α4β2 Nicotinic Receptor Subtype

5. Indolizidine and quinolizidine alkaloids

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