Divergent access to N-hydroxypyrroles and isoxazoles via the gold(i)- or Brønsted acid-catalysed regioselective cyclization of N-(2-trifluoromethyl-3-alkynyl) oximes
Author:
Affiliation:
1. Department of Chemistry
2. School of Chemistry and Molecular Engineering
3. East China Normal University
4. Shanghai
5. P. R. China
Abstract
The divergent regioselective cyclization of N-(2-trifluoromethyl-3-alkynyl) oximes by a suitable choice of a gold(i) or Brønsted acid catalyst, leading to N-hydroxypyrroles or Isoxazoles was developed.
Funder
National Natural Science Foundation of China
Science and Technology Commission of Shanghai Municipality
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/OB/C7OB03107F
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5. Novel Class of Potent 4-Arylalkyl Substituted 3-Isoxazolol GABAA Antagonists: Synthesis, Pharmacology, and Molecular Modeling
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