Perylenediimide-based glycoclusters as high affinity ligands of bacterial lectins: synthesis, binding studies and anti-adhesive properties

Author:

Donnier-Maréchal Marion12345,Galanos Nicolas12345,Grandjean Teddy67895,Pascal Yoann12345,Ji Ding-Kun1011121314,Dong Lei12345,Gillon Emilie1516175,He Xiao-Peng1011121314,Imberty Anne1516175,Kipnis Eric67895,Dessein Rodrigue67895,Vidal Sébastien12345ORCID

Affiliation:

1. Institut de Chimie et Biochimie Moléculaires et Supramoléculaires

2. Laboratoire de Chimie Organique 2 – Glycochimie UMR 5246

3. CNRS – Université Claude Bernard Lyon 1

4. F-69622 Villeurbanne

5. France

6. Université de Lille

7. CHU Lille

8. Recherche Translationnelle: Relations Hôte-Pathogènes (EA 7366)

9. F-59000 Lille

10. Key Laboratory for Advanced Materials & Institute of Fine Chemicals

11. School of Chemistry and Molecular Engineering

12. East China University of Science and Technology

13. Shanghai 200237

14. China

15. Centre de Recherche sur les Macromolécules Végétales (CERMAV)

16. CNRS and Université Grenoble Alpes

17. F-38041 Grenoble

Abstract

Rapid access to perylenediimide-based glycoclusters allowed their evaluation as high affinity ligands of bacterial lectins and their potential as anti-adhesive antibacterials.

Funder

Agence Nationale de la Recherche

China Scholarship Council

Association Vaincre la Mucoviscidose

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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