In vitro anticancer activity of AIEgens

Author:

Yin Feng12345ORCID,Gu Bobo6789ORCID,Li Jingxu12345,Panwar Nishtha10111213ORCID,Liu Yong1415161718,Li Zigang12345,Yong Ken-Tye10111213ORCID,Tang Ben Zhong1415161718ORCID

Affiliation:

1. State Key Laboratory of Chemical Oncogenomics

2. Key Laboratory of Chemical Genomics

3. School of Chemical Biology and Biotechnology

4. Peking University Shenzhen Graduate School

5. Shenzhen

6. Med-X Research Institute and School of Biomedical Engineering

7. Shanghai Jiao Tong University

8. Shanghai 200030

9. China

10. School of Electrical and Electronic Engineering

11. Nanyang Technological University

12. Singapore 639798

13. Singapore

14. Department of Chemistry

15. HKUST Jockey Club Institute for Advanced Study

16. Institute of Molecular Functional Materials

17. Division of Biomedical Engineering

18. State Key Laboratory of Molecular Neuroscience

Abstract

AIEgens possess superior cytotoxicity, tumor invasion, and hemolysis against cancer cells and cancer stem cells. Simple structural modifications enable them as highly biocompatible, image-guided chemotherapy agents.

Funder

National Natural Science Foundation of China

Science and Technology Commission of Shanghai Municipality

Ministry of Education - Singapore

National Research Foundation Singapore

Economic Development Board - Singapore

Nanyang Technological University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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