Magnetic nanomaterials with near-infrared pH-activatable fluorescence via iron-catalyzed AGET ATRP for tumor acidic microenvironment imaging-Reference-Cited by-同舟云学术

Magnetic nanomaterials with near-infrared pH-activatable fluorescence via iron-catalyzed AGET ATRP for tumor acidic microenvironment imaging

Published:2015 Issue:14 Volume:3 Page:2786-2800
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Liu Xiaodong¹²³⁴⁵,Chen Qian⁶⁷⁸⁹¹⁰,Yang Guangbao⁶⁷⁸⁹¹⁰,Zhang Lifen¹²³⁴⁵,Liu Zhuang⁶⁷⁸⁹¹⁰,Cheng Zhenping¹²³⁴⁵,Zhu Xiulin¹²³⁴⁵

Affiliation:

1. Suzhou Key Laboratory of Macromolecular Design and Precision Synthesis

2. Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application

3. Department of Polymer Science and Engineering

4. College of Chemistry

5. Chemical Engineering and Materials Science

6. Institute of Functional Nano and Soft Materials (FUNSOM)

7. Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices

8. Soochow University

9. Suzhou 215123

10. China

Abstract

This work provides a fluorescent/magnetic iron oxide nanomaterials prototype to visualize the solid tumor in vivo by sensing the tumor acidic microenvironment, and a satisfactory tumor-to-normal tissue signal ratio (T/N ratio) and a prolonged time-window for 4T1 tumor visualization were observed in vivo.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2015/TB/C5TB00070J

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