Dissolving microneedle-encapsulated drug-loaded nanoparticles and recombinant humanized collagen type III for the treatment of chronic wound <i>via</i> anti-inflammation and enhanced cell proliferation and angiogenesis-Reference-Cited by-同舟云学术

Dissolving microneedle-encapsulated drug-loaded nanoparticles and recombinant humanized collagen type III for the treatment of chronic wound via anti-inflammation and enhanced cell proliferation and angiogenesis

Published:2022 Issue:4 Volume:14 Page:1285-1295
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Long Lin-yu¹^ORCID,Liu Wenqi¹,Li Li²,Hu Cheng¹^ORCID,He Shuyi¹,Lu Lu³,Wang Jian⁴,Yang Li¹,Wang Yun-bing¹^ORCID

Affiliation:

1. National Engineering Research Center for Biomaterials, Chuanda-Jinbo Joint Research Center, Sichuan University, Chengdu, 610064, China

2. Institute of Clinical Pathology, West China Hospital of Sichuan University, Chengdu, 610041, China

3. Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Fudan-Jinbo Joint Research Center, Fudan University, Shanghai, 200302, China

4. Shanxi Jinbo Bio-Pharmaceutical Co., Ltd, Taiyuan, 030032, China

Abstract

The first recombinant humanized collagen type III (rhCol III) and naproxen (Nap) loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles incorporated hyaluronic acid (HA) microneedle (MN) was fabricated for diabetic chronic wounds therapy.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Project 211

Fundamental Research Funds for the Central Universities

West China Hospital, Sichuan University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NR/D1NR07708B