Co-immobilised 7α- and 7β-HSDH as recyclable biocatalyst: high-performance production of TUDCA from waste chicken bile-Reference-Cited by-同舟云学术

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Co-immobilised 7α- and 7β-HSDH as recyclable biocatalyst: high-performance production of TUDCA from waste chicken bile

Published:2018 Issue:60 Volume:8 Page:34192-34201
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ji Qingzhi¹²³⁴^ORCID,Wang Bochu⁵⁶⁷⁸⁹^ORCID,Li Chou¹⁰²³⁴,Hao Jinglan¹²³⁴,Feng Wenjing¹²³⁴

Affiliation:

1. School of Pharmacy

2. Yancheng Teachers' University

3. Yancheng

4. P. R. China

5. Key Laboratory of Biorheological Science and Technology (Chongqing University)

6. Ministry of Education

7. College of Bioengineering

8. Chongqing University

9. Chongqing 400030

10. College of Marine and Bio-engineering

Abstract

TUDCA was prepared using chicken bile as substrate with the catalysis of co-immobilised 7α- and 7β-HSDH.

Funder

Chongqing University

Ministry of Education of the People's Republic of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA06798H

Reference34 articles.

1. Bile salt biotransformations by human intestinal bacteria

2. Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha

3. TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCezrin pathway

4. Tauroursodeoxycholic acid inhibits intestinal inflammation and barrier disruption in mice with non-alcoholic fatty liver disease

5. Tauroursodeoxycholic acid prevents hearing loss and hair cell death in Cdh23 mice

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1. Safety assessment of enzymatically converted chicken bile as a novel food material: Genotoxicity, teratogenicity, and acute and subchronic toxicity studies;Journal of Food Science;2024-06-26

2. Biotransformed bear bile powder alleviates diet-induced nonalcoholic fatty liver disease in mice by regulating the gut microbiota and reversing lipid metabolism;Arabian Journal of Chemistry;2024-02

3. Engineering the cofactor binding site of 7α-hydroxysteroid dehydrogenase for improvement of catalytic activity, thermostability, and alteration of substrate preference;International Journal of Biological Macromolecules;2024-02

4. Biotransformed bear bile powder ameliorates diet-induced nonalcoholic steatohepatitis in mice through modulating arginine biosynthesis via FXR/PXR-PI3K-AKT-NOS3 axis;Biomedicine & Pharmacotherapy;2023-12

5. Design of St-2-2 7α-HSDH mutants for altering substrate preference and thermostability;Molecular Catalysis;2023-09

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