Catalytic approach to in vivo metabolism of atractylenolide III using biomimetic iron–porphyrin complexes-Reference-Cited by-同舟云学术

Catalytic approach to in vivo metabolism of atractylenolide III using biomimetic iron–porphyrin complexes

Published:2021 Issue:52 Volume:11 Page:33048-33054
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Lim Hanae¹,Jeon Hyeri¹,Hong Seungwoo¹,Kim Jung-Hoon²^ORCID

Affiliation:

1. Department of Chemistry, The Research Institute of Natural Sciences, Sookmyung Women's University, 04310, Seoul, Republic of Korea

2. Division of Pharmacology, School of Korean Medicine, Pusan National University, 50612, Yangsan, Republic of Korea

Abstract

In vivo oxygenation of atractylenolide III during the metabolism and in situ oxidation mechanism by an iron–porphyrin iron(iv)-oxo porphyrin π-cation–radical complex.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA05014A

Reference43 articles.

1. The Anticancer Effects of Atractylenolide III Associate With the Downregulation of Jak3/Stat3-Dependent IDO Expression

2. Atractylenolide III ameliorates cerebral ischemic injury and neuroinflammation associated with inhibiting JAK2/STAT3/Drp1-dependent mitochondrial fission in microglia

3. Anti-inflammatory activity of atractylenolide III through inhibition of nuclear factor-κB and mitogen-activated protein kinase pathways in mouse macrophages

4. Quantitative Interrelation between Atractylenolide I, II, and III in Atractylodes japonica Koidzumi Rhizomes, and Evaluation of Their Oxidative Transformation Using a Biomimetic Kinetic Model

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