The application of NH<sub>4</sub>SCN as a nontoxic cyanide source for the divergent Strecker synthesis of aminonitriles and iminonitriles-Reference-Cited by-同舟云学术

The application of NH₄SCN as a nontoxic cyanide source for the divergent Strecker synthesis of aminonitriles and iminonitriles

Published:2023 Issue:4 Volume:10 Page:1009-1014
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wang Xiaofan¹,Zhao Bingyue¹,Xu Lingzhi¹,Li Xuemin¹,Shi Haofeng¹,Du Yunfei¹^ORCID

Affiliation:

1. School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China

Abstract

The reaction of arylaldehydes and arylamines with nontoxic NH4SCN in the presence of TBHP led to a divergent Strecker synthesis of aminonitriles and iminonitriles.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D2QO01692C

Reference48 articles.

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2. R. C.Larock , Comprehensive organic transformations: a guide to functional group preparations , VCH , 1989

3. A molecular shuttle for hydrogen cyanide

4. Cyano Groups as Probes of Protein Microenvironments and Dynamics

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