PhpC modulates G-quadruplex-RNA landscapes in human cells-Reference-Cited by-同舟云学术

PhpC modulates G-quadruplex-RNA landscapes in human cells

Published:2024 Issue:4 Volume:60 Page:424-427
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Mitteaux Jérémie¹,Raevens Sandy¹,Wang Zi²,Pirrotta Marc¹,Valverde Ibai E.¹,Hudson Robert H. E.²^ORCID,Monchaud David¹^ORCID

Affiliation:

1. Institut de Chimie Moléculaire de l’Université de Bourgogne (ICMUB), CNRS UMR 6302, 9, avenue Alain Savary, Dijon 21078, France

2. Department of Chemistry, The University of Western Ontario, London, ON N6A 5B7, Canada

Abstract

The ability of the phenylpyrrolocytosine (PhpC) small molecule to unfold G-quadruplex (G4) nucleic acids in human cells is demonstrated here both qualitaOvely and quanOtaOvely.

Funder

Agence Nationale de la Recherche

Institut de chimie

Ligue Contre le Cancer

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D3CC05155B

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