Multivariate analysis applied to complex biological medicines

Author:

Rudd Timothy R.12345ORCID,Mauri Lucio678,Marinozzi Maria678,Stancanelli Eduardo678,Yates Edwin A.459103ORCID,Naggi Annamaria678,Guerrini Marco678ORCID

Affiliation:

1. National Institute for Biological Standards and Control (NIBSC)

2. Potters Bar

3. UK

4. Department of Biochemistry

5. Biosciences Building

6. Istituto di Ricerche Chimiche e Biochimiche ‘G. Ronzoni’

7. 20133 Milano

8. Italy

9. University of Liverpool

10. Liverpool

Abstract

Principal component analysis of 13C–1H HSQC NMR spectra allows heparin from different animal sources to be differentiated, as well as spectral features that are specific to each heparin type to be identified.

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry

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