Bifunctional cysteine gold nanoclusters for β-amyloid fibril inhibition and fluorescence imaging: a distinctive approach to manage Alzheimer's disease-Reference-Cited by-同舟云学术

Bifunctional cysteine gold nanoclusters for β-amyloid fibril inhibition and fluorescence imaging: a distinctive approach to manage Alzheimer's disease

Published:2023 Issue:21 Volume:11 Page:4715-4724
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Resmi A. N.¹,Rekha C. R.¹,Dhushyandhun M. E.¹,Elangovan Sarathkumar¹,Shenoy Sachin J.²,Gulia Kamalesh K.³,Jayasree Ramapurath S.¹^ORCID

Affiliation:

1. Division of Biophotonics and Imaging, Department of Biomaterial Sciences and Technology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum 695012, India

2. Division of in vivo Models and Testing, Department of Applied Biology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum 695012, India

3. Division of Sleep Research, Department of Applied Biology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum 695012, India

Abstract

l-Dopa conjugated cysteine-gold nanoclusters (AuCs-LD) can cross the blood–brain barrier and disintegrate Aβ plaques, demonstrating a potential therapeutic for the management of Alzheimer's disease.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

Science for Equity, Empowerment and Development Division

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D2TB02802F

Reference53 articles.

1. A Review of the Common Neurodegenerative Disorders: Current Therapeutic Approaches and the Potential Role of Nanotherapeutics

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