Copper-mediated oxidative [3 + 2]-annulation of nitroalkenes and pyridinium ylides: general access to functionalized indolizines and efficient synthesis of 1-fluoroindolizines

Author:

Motornov Vladimir A.12345ORCID,Tabolin Andrey A.1234ORCID,Nelyubina Yulia V.6234ORCID,Nenajdenko Valentine G.7894ORCID,Ioffe Sema L.1234ORCID

Affiliation:

1. N. D. Zelinsky Institute of Organic Chemistry

2. Russian Academy of Sciences

3. Moscow

4. Russia

5. Higher Chemical College

6. A. N. Nesmeyanov Institute of Organoelement Compounds

7. Department of Chemistry

8. M. V. Lomonosov Moscow State University

9. Moscow 119991

Abstract

Novel 1-fluoroindolizines were obtained via copper(ii)-mediated oxidative [3 + 2]-annulation of in situ generated pyridinium ylides and fluoronitroalkenes.

Funder

Russian Foundation for Basic Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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