Oral administration of Lentinus edodes β-glucans ameliorates DSS-induced ulcerative colitis in mice via MAPK-Elk-1 and MAPK-PPARγ pathways-Reference-Cited by-同舟云学术

Oral administration of Lentinus edodes β-glucans ameliorates DSS-induced ulcerative colitis in mice via MAPK-Elk-1 and MAPK-PPARγ pathways

Published:2016 Issue:11 Volume:7 Page:4614-4627
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Shi Limin¹²³⁴⁵,Lin Qinlu¹²³⁴⁵,Yang Tao¹²³⁴⁵,Nie Ying¹²³⁴⁵,Li Xinhua⁶⁷⁸⁵⁹,Liu Bo¹²³⁴⁵,Shen Junjun¹²³⁴⁵,Liang Ying¹²³⁴⁵,Tang Yiping¹²³⁴⁵,Luo Feijun¹²³⁴⁵

Affiliation:

1. Laboratory of Molecular Nutrition

2. College of Food Science and Engineering

3. National Engineering Laboratory for Rice and Byproduct Deep Processing

4. Central South University of Forestry and Technology

5. Changsha

6. Department of Gastroenterology

7. Xiangya Hospital

8. Central South University

9. PR China

Abstract

To evaluate the anti-inflammatory effect of β-glucans fromLentinus edodes, and its molecular mechanism, the dextran sulfate sodium salt (DSS) induced colitis model of mice and the LPS-stimulated RAW264.7 cell inflammation model were used in this study.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2016/FO/C6FO01043A

Reference68 articles.

1. Inflammation as a tumor promoter in cancer induction

2. Overexpression of PAK1 Promotes Cell Survival in Inflammatory Bowel Diseases and Colitis-associated Cancer

3. Inflammatory bowel disease: clinical aspects and established and evolving therapies

4. The immunological and genetic basis of inflammatory bowel disease

5. Kolaviron, a natural flavonoid from the seeds of Garcinia kola, reduces LPS-induced inflammation in macrophages by combined inhibition of IL-6 secretion, and inflammatory transcription factors, ERK1/2, NF-κB, p38, Akt, p-c-JUN and JNK

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