Enhanced relaxivity of GdIII-complexes with HP-DO3A-like ligands upon the activation of the intramolecular catalysis of the prototropic exchange-Reference-Cited by-同舟云学术

Enhanced relaxivity of GdIII-complexes with HP-DO3A-like ligands upon the activation of the intramolecular catalysis of the prototropic exchange

Published:2021 Issue:6 Volume:8 Page:1500-1510
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Lattuada Luciano¹²³⁴^ORCID,Horváth Dávid⁵⁶⁷⁸^ORCID,Colombo Serra Sonia⁹¹⁰⁴,Fringuello Mingo Alberto⁹¹⁰⁴^ORCID,Minazzi Paolo¹¹¹²⁴^ORCID,Bényei Attila⁵⁶⁷⁸^ORCID,Forgács Attila¹³¹⁴⁸,Fedeli Franco¹¹¹²⁴,Gianolio Eliana¹⁵¹⁶¹⁷⁴^ORCID,Aime Silvio¹⁵¹⁶¹⁷⁴^ORCID,Giovenzana Giovanni B.¹¹¹²⁴¹⁸¹⁹^ORCID,Baranyai Zsolt⁹¹⁰⁴^ORCID

Affiliation:

1. Innovation Hub

2. Bracco SpA

3. 20134 Milano

4. Italy

5. Department of Physical Chemistry

6. University of Debrecen

7. Debrecen, Egyetem tér 1.

8. Hungary

9. Bracco Research Center

10. 10010 Colleretto

11. CAGE Chemicals

12. 28100 Novara

13. MTA-DE Redox and Homogeneous Catalytic Reaction Mechanisms Research Group

14. Debrecen

15. Department of Molecular Biotechnologies and Health Science

16. University of Turin

17. Turin

18. Dipartimento di Scienze del Farmaco

19. Università del Piemonte Orientale

Abstract

The simple modification of the hydroxypropyl arm in Gd(HP-DO3A) complex allows to achieve an increased relaxivity by the activation of the intramolecular catalysis of the proton exchange process.

Funder

Nemzeti Kutatási Fejlesztési és Innovációs Hivatal

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QI/D0QI01333A

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