MiR-146a encapsulated liposomes reduce vascular inflammatory responses through decrease of ICAM-1 expression, macrophage activation, and foam cell formation-Reference-Cited by-同舟云学术

MiR-146a encapsulated liposomes reduce vascular inflammatory responses through decrease of ICAM-1 expression, macrophage activation, and foam cell formation

Published:2023 Issue:7 Volume:15 Page:3461-3474
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Ho Donald¹^ORCID,Lynd Tyler O.²,Jun Claire³,Shin Juhee⁴^ORCID,Millican Reid C.⁵^ORCID,Estep Benjamin K.²,Chen Jun²,Zhang Xixi²^ORCID,Brott Brigitta C.⁵⁶,Kim Dong Woon⁴^ORCID,Sherwood Jennifer A.⁵,Hwang Patrick T. J.²⁵^ORCID

Affiliation:

1. Department of Pediatric Dentistry, University of Alabama at Birmingham, AL, 35294, USA

2. Department of Biomedical Engineering, University of Alabama at Birmingham, AL, 35294, USA

3. School of Arts and Sciences, University of Pennsylvania, PA, 19104, USA

4. Department of Anatomy and Cell Biology, Brain Research Institute, Chungnam National University College of Medicine, Daejeon, 35015, Republic of Korea

5. Endomimetics, LLC, Birmingham, AL, 35242, USA

6. Department of Medicine and Division of Cardiovascular Disease, University of Alabama at Birmingham, AL, 35233, USA

Abstract

Treatment of microRNA-146a encapsulated liposomes reduces vascular inflammation by targeting multiple related components including endothelial cell, smooth muscle cell, and macrophage activation as well as foam cell formation.

Funder

National Heart, Lung, and Blood Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NR/D2NR03280E

Reference56 articles.

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