Asymmetric synthesis of α-deuterated α-amino acids-Reference-Cited by-同舟云学术

Asymmetric synthesis of α-deuterated α-amino acids

Published:2017 Issue:33 Volume:15 Page:6978-6983
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Takeda Ryosuke¹²³⁴⁵^ORCID,Abe Hidenori¹²³^ORCID,Shibata Norio⁶⁷⁸³^ORCID,Moriwaki Hiroki¹²³^ORCID,Izawa Kunisuke¹²³^ORCID,Soloshonok Vadim A.⁴⁵⁹¹⁰¹¹^ORCID

Affiliation:

1. Hamari Chemicals Ltd.

2. Osaka 533-0024

3. Japan

4. Department of Organic Chemistry I

5. Faculty of Chemistry

6. Department of Nanopharmaceutical Science & Department of Frontier Materials

7. Nagoya Institute of Technology

8. Nagoya

9. University of the Basque Country UPV/EHU

10. 20018 San Sebastián

11. Spain

Abstract

A generalized approach for the preparation of α-²H-α-amino acids in enantiomerically pure form and with up to 99% deuteration is disclosed.

Funder

Ikerbasque, Basque Foundation for Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01720K

Reference104 articles.

1. Stereochemically defined C-substituted glutamic acids and their derivatives. 1. An efficient asymmetric synthesis of (2S,3S)-3-methyl- and -3-trifluoromethylpyroglutamic acids

2. The synthesis of peptides and proteins containing non-natural amino acids

3. Tailor-Made α-Amino Acids in the Pharmaceutical Industry: Synthetic Approaches to (1R,2S)-1-Amino-2-vinylcyclopropane-1-carboxylic Acid (Vinyl-ACCA)

4. Practical synthesis of fluorine-containing α- and β-amino acids: recipes from Kiev, Ukraine

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