Palladium-catalyzed Heck/aminocarbonylation of alkene-tethered carbamoyl chlorides with nitro compounds for the synthesis of carbamoyl-substituted oxindoles-Reference-Cited by-同舟云学术

Palladium-catalyzed Heck/aminocarbonylation of alkene-tethered carbamoyl chlorides with nitro compounds for the synthesis of carbamoyl-substituted oxindoles

Published:2023 Issue:30 Volume:21 Page:6107-6110
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Pan Xing-Feng¹,Bao Xuanzhang¹,Xu Ren-Rui¹,Qi Xinxin¹,Wu Xiao-Feng²³^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering, Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, People's Republic of China

2. Dalian National Laboratory for Clean Energy, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 116023, Dalian, Liaoning, China

3. Leibniz-Institut für Katalyse e.V., Albert-Einstein-Straße 29a, Rostock 18059, Germany

Abstract

A new approach for the synthesis of carbamoyl-substituted oxindoles has been developed via a palladium-catalyzed Heck cyclization and reductive aminocarbonylation reaction of alkene-tethered carbamoyl chlorides with nitro compounds.

Funder

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01004J

Reference43 articles.

1. Oxindole and its derivatives: A review on recent progress in biological activities

2. Structural insights of oxindole based kinase inhibitors as anticancer agents: Recent advances

3. Review of synthesis and various biological activities of spiro heterocyclic compounds comprising oxindole and pyrrolidine moities