Benzylidene-linked thiohydantoin derivatives as inhibitors of tyrosinase and melanogenesis: importance of the β-phenyl-α,β-unsaturated carbonyl functionality
Author:
Affiliation:
1. Molecular Inflammation Research Center for Aging Intervention (MRCA)
2. College of Pharmacy
3. Pusan National University
4. Busan 609-735, Republic of Korea
5. Inje University
6. Gimhae, Republic of Korea
Abstract
The “β-phenyl-α,β-unsaturated carbonyl” group might serve as a key pharmacophore for high tyrosinase inhibition.
Publisher
Royal Society of Chemistry (RSC)
Subject
Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/MD/C4MD00171K
Reference23 articles.
1. Enzymatic control of pigmentation in mammals
2. Polyphenol oxidases in plants
3. J. R. Whitaker , Polyphenol Oxidase , in Food Enzyme: Structure and Mechanism ; ed. D. W. S. Wong , Chapman & Hall , New York , 1995 , pp. 271–307
4. The Protective Role of Melanin Against UV Damage in Human Skin†
5. An Enzyme-Initiated Hydroxylation-Oxidation Carbo Diels-Alder Domino Reaction
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