Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux-Reference-Cited by-同舟云学术

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

Published:2019 Issue:6 Volume:10 Page:901-906
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Stone M. Rhia L.¹²³⁴^ORCID,Masi Muriel⁵⁶⁷⁸⁹^ORCID,Phetsang Wanida¹²³⁴^ORCID,Pagès Jean-Marie⁵⁶⁷⁸⁹^ORCID,Cooper Matthew A.¹²³⁴^ORCID,Blaskovich Mark A. T.¹²³⁴^ORCID

Affiliation:

1. Institute for Molecular Bioscience

2. The University of Queensland

3. Brisbane

4. Australia

5. Membranes et Cibles Thérapeutiques

6. UMR_MD1

7. Inserm U1261

8. Aix-Marseille Univ & IRBA

9. Facultés de Médecine et de Pharmacie

Abstract

Fluorescent probes derived from the fluoroquinolone antibiotic ciprofloxacin were synthesised using a Cu(i)-catalysed azide–alkyne cycloaddition (CuAAC) to link a ciprofloxacin azide derivative with alkyne-substituted green and blue fluorophores.

Funder

National Health and Medical Research Council

Wellcome Trust

Campus France

University of Queensland

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C9MD00124G

Reference36 articles.