Facile preparation of injectable, thermosensitive, and physically cross-linked hemostatic hydrogel with rapid gelation and a robust network

Author:

Wang Xue1,Liu Wentao2ORCID,Wang Yue1,Hou Zhaosheng3ORCID,She Pengbo1,Yang Yaozhen1,Li Xiuxiu1,Wang Xiaolong4,Liu Jintong1,Liu Xiangzheng1,Xu Jing1

Affiliation:

1. Shandong Provincial Key Laboratory of Molecular Engineering, School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, P. R. China

2. Key Laboratory of Leather Chemistry and Engineering of Ministry of Education, College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, P. R. China

3. College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan 250100, P. R. China

4. Laboratory Management Office, Shandong University of Traditional Chinese Medicine, Jinan 250353, P. R. China

Abstract

A thermosensitive, double-network hemostatic hydrogel with rapid gelation and a robust network was facilely prepared by blending gelatin, hyaluronic-acid, and linear-poly-N-isopropylacrylamide.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Qilu University of Technology

Science and Technology Support Plan for Youth Innovation of Colleges and Universities of Shandong Province of China

Publisher

Royal Society of Chemistry (RSC)

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