Synthesis, biological evaluation and <i>in silico</i> studies of 1,2,3-triazolyl-metronidazole derivatives against <i>Leishmania major</i>-Reference-Cited by-同舟云学术

Synthesis, biological evaluation and in silico studies of 1,2,3-triazolyl-metronidazole derivatives against Leishmania major

Published:2022 Issue:18 Volume:46 Page:8451-8463
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Ghanbariasad Ali¹,Emami Leila²,Zarenezhad Elham³^ORCID,Behrouz Somayeh⁴,Zarenezhad Ali³,Rad Mohammad Navid Soltani⁴

Affiliation:

1. Department of Medical Biotechnology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran

2. Pharmaceutical Sciences, Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

3. Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran

4. Medicinal Chemistry Research Laboratory, Department of Chemistry, Shiraz University of Technology, Shiraz 71555-313, Iran

Abstract

The synthesis of novel 1,2,3-triazolyl-based metronidazole hybrid analogues as potent anti-Leishmania agents using [CuL-SiO-HA] as a catalyst has been described.

Funder

Fasa University of Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ00226D

Reference51 articles.

1. Drug resistance in Indian visceral leishmaniasis

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