Sugar hydrazide imides: a new family of glycosidase inhibitors

Author:

Lindbäck Emil12345ORCID,Lopéz Óscar6789ORCID,Tobiesen Ådne12345,Fernández-Bolaños José G.6789ORCID,Sydnes Magne O.12345ORCID

Affiliation:

1. Faculty of Science and Technology

2. Department of Mathematics and Natural Science

3. University of Stavanger

4. NO-4036 Stavanger

5. Norway

6. Department of Organic Chemistry

7. University of Seville

8. 41012 Seville

9. Spain

Abstract

We present a new type of glycosidase inhibitor including a unique hydrazide imide moiety, which displays inhibition in the low micromolar range.

Funder

Dirección General de Investigación Científica y Técnica

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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