Synthesis, biological evaluation, and in silico studies of novel chalcone- and pyrazoline-based 1,3,5-triazines as potential anticancer agents-Reference-Cited by-同舟云学术

Synthesis, biological evaluation, and in silico studies of novel chalcone- and pyrazoline-based 1,3,5-triazines as potential anticancer agents

Published:2020 Issue:56 Volume:10 Page:34114-34129
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Moreno Leydi M.¹²³⁴⁵,Quiroga Jairo¹²³⁴⁵,Abonia Rodrigo¹²³⁴⁵,Lauria Antonino⁶⁷⁸⁹,Martorana Annamaria⁶⁷⁸⁹,Insuasty Henry¹²¹⁰¹¹⁵^ORCID,Insuasty Braulio¹²³⁴⁵^ORCID

Affiliation:

1. Heterocyclic Compounds Research Group

2. Department of Chemistry

3. Universidad del Valle

4. A.A. 25360 Cali

5. Colombia

6. Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche “STEBICEF”

7. Università di Palermo

8. I-90128 Palermo

9. Italy

10. Universidad de Nariño

11. A.A. 1175 Pasto

Abstract

A novel series of triazin-chalcones (7,8)a–g and triazin-N-(3,5-dichlorophenyl)pyrazolines (9,10)a–g were synthesized and evaluated for their anticancer activity against nine different cancer strains.

Funder

Departamento Administrativo de Ciencia, Tecnología e Innovación

Universidad del Valle

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA06799G

Reference51 articles.

1. Heterocyclic Anticancer Compounds: Recent Advances and the Paradigm Shift towards the Use of Nanomedicine’s Tool Box

2. Anticancer platinum(II) complexes bearing N-heterocycle rings