Adsorption of lysozyme into a charged confining pore-Reference-Cited by-同舟云学术

Adsorption of lysozyme into a charged confining pore

Published:2021 Issue:48 Volume:23 Page:27195-27206
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Caetano Daniel L. Z.¹²^ORCID,Metzler Ralf³^ORCID,Cherstvy Andrey G.³⁴^ORCID,de Carvalho Sidney J.⁵^ORCID

Affiliation:

1. Institute of Chemistry, State University of Campinas (UNICAMP), Campinas, Brazil

2. Center for Computational Engineering and Sciences, State University of Campinas (UNICAMP), Campinas, Brazil

3. Institute for Physics & Astronomy, University of Potsdam, 14476 Potsdam-Golm, Germany

4. Institut für Physik, Humboldt-Universität zu Berlin, 12489 Berlin, Germany

5. Department of Physics, São Paulo State University (UNESP), Institute of Biosciences, Humanities and Exact Sciences, São José do Rio Preto, Brazil

Abstract

The hen egg-white lysozyme adsorbs into a charged confining pore in two orientations depending on the pH. The pKa of the residues closer to the pore surface is significantly affected by the protein–pore electrostatic interactions.

Funder

Fundacja na rzecz Nauki Polskiej

Fundação de Amparo à Pesquisa do Estado de São Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Universidade Estadual Paulista

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CP/D1CP03185F

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1. Mesoporous silica-based nanodevices for biological applications

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4. Mesoporous Silica Nanoparticles as a Delivery System for Hydrophobic Anticancer Drugs

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